Affected individuals may sleep for up to 20 hours per day during an episode. up to 20 hours a day); excessive food intake (compulsive hyperphagia ); and an abnormally uninhibited sexual drive. ABSTRACTINTRODUCTION: Kleine-Levin syndrome is a rare neurological disorder (1-2 cases per million inhabitants) primarily affecting young subjects. Kleine-Levin Syndrome (KLS), also known as "Sleeping Beauty" syndrome, is a rare neurological disorder characterised by recurrent bouts of hypersomnolence (excessive sleeping) along with cognitive and behavioural problems during wakefulness. The patients have recurrent episodes of hypersomnia, which are often associated with . Symptoms occur in cycles that can last anywhere from a few days to several weeks. In 1862, Brierre de Boismont reported the … Someone who has Kleine-Levin syndrome may sleep for up to 20 hours a day, eat excessive amounts of food, or behave in an abnormal and overly sexual way. The Kleine-Levin syndrome is a rare pathology characterized by recurrent episodes of hypersomnia associated with behavioral and cognitive disorders with, among others, hyperphagia and hypersexuality. Kleine-Levin syndrome (KLS) is a rare sleep disorder mainly affecting teenage boys in which the main features are intermittent hypersomnolence, behavioral and cognitive disturbances, hyperphagia, and in some cases hyper sexuality. It's characterized by recurring periods of excessive sleepiness and cognitive troubles that come and go over the course of many years. Health. Kleine-Levin syndrome (KLS) is a rare disorder that causes recurring periods of excessive sleepiness. Diagnosing Kleine-Levin Syndrome. 克萊恩-萊文症候群（英語： Kleine-Levin syndrome ，简称为KLS），又名睡美人症候群（英語： Sleeping Beauty syndrome ），是一種不常見的睡眠障礙，特徵是持續的陣發過度嗜睡症及認知或情緒變化。 許多患者會有食量變大、性慾亢進，或是其他症狀；患者往往會反覆發作症狀長達十年以上，且日後可能會再 . Kleine Levin Syndrome is a hypersomnia, a sleep disorder in which the afflicted experience periods of excessive sleeping. Objective To retrospectively compare the benefits (episode cessation) and risks of IV methylprednisolone (IV-MP) vs abstention during prolonged Kleine-Levin syndrome (KLS) episodes. The victims of this disorder often also experience excessive appetite (hyperphagia), increased sexual urges (hypersexuality) and dramatic mood swings. The Kleine-Levin syndrome is a medical condition, in which the patient suffers from episodes of hypersomnia, accompanied by changes in the cognitive function or mood. Patients generally experience recurrent episodes of the condition for more than a decade and may return at a later age. Kleine-Levin Syndrome ("KLS") is a rare sleep disorder characterized by recurrent episodes of hypersomnia lasting one to 3 weeks, associated with behavioral/cognitive disturbances, megaphagia and, more rarely, sexual disinhibition. Diagnosing KLS is admittedly a challenge but can be a relief for a family in search of answers. The behavioral disturbances can be composed of hyperphagia, irritability, or sexual disinhibition. Kleine-Levin syndrome (KLS) is a rare neurological disorder of unknown origin characterised by relapsing-remitting episodes of hypersomnia in association with cognitive and behavioural disturbances. Symptoms occur as "episodes," typically lasting a few days to a few weeks. The first episode usually begins within a few hours, with patients becoming extremely tired, generally after an identifiable triggering event, such as a banal infection in most cases, alcohol intake, or a head trauma. Other characteristics include bouts of intense hunger and strong sexual desire. Kleine-Levin syndrome, or KLS, is a rare disorder associated with extreme fatigue and excessive sleepiness, causing patients to sleep as much as 20 hours a day. Kleine-Levin syndrome (KLS) is a very uncommon sleep disorder. Other characteristics include bouts of intense hunger and strong sexual desire. Because its primary symptom, hypersomnia, is common to a number of disorders, the process by which we diagnose KLS is one of exclusion - ruling out other conditions that share symptoms. Kleine Levin Syndrome Awareness Brain Disease Related Papa B Raglan Baseball Tee 1 offer from $23.99 Kleine Levin Syndrome Awareness Brain Disease Related Papa B Premium T-Shirt Methods: We collected detailed clinical data and blood samples on 108 patients, 79 parent pairs, and 108 matched control subjects. In this article, we discuss the causes, symptoms, and best treatment for Kleine Levin syndrome. Objective: Kleine-Levin syndrome is a rare disorder characterized by relapsing-remitting episodes of hypersomnia, cognitive disturbances, and behavioral disturbances, such as hyperphagia and hypersexuality. Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male). These episodes may also be associated with . Kleine-Levin syndrome (KLS) is a rare, relapsing-remitting disease that affects mostly adolescents. Kleine-Levin syndrome is a rare disorder that causes a person to sleep excessively. While experiencing symptoms, patients sleep most of the day and night. This condition is also known as the Sleeping Beauty syndrome, being considered a rare sleep disorder. Kleine-Levin syndrome, sometimes referred to as Rip van Winkle disease, is a rare sleep disorder mainly affecting teenage boys in which the main features are intermittent hypersomnolence, behavioural and cognitive disturbances, hyperphagia and in some cases hypersexuality. Kleine Levin syndrome symptoms. Kleine-Levin syndrome (KLS) is a rare neurological disorder characterized by episodes of excessive need for sleep that occur weeks or months apart. By continuing to browse this site you are agreeing to our use of cookies. Each episode is of brief duration varying from a week to 1-2 months and affected people are entirely . Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male). Kleine-Levin syndrome or sleeping beauty syndrome is a neurological disorder characterized by recurring episodes of an excessive amount of sleeping and eating. Kleine-Levin Syndrome. Kleine-Levin syndrome is characterized by the association of episodes of hypersomnias with behavioral, cognitive and mood abnormalities. By continuing to browse this site you are agreeing to our use of cookies. My 16 year old son was recently diagnosed with Kleine-Levin Syndrome (KLS). While experiencing symptoms, patients sleep most of the day and night. Pathophysiologic hypotheses include a hypothalamic dysfunction and abnormalities in the central serotonin and dopamine metabolism. Kleine-Levin Syndrome (KLS), also known as "Sleeping Beauty Syndrome", is a rare and complex neurological disorder that is characterized by periods of excessive sleep (hypersomnia; up to 20 hours . At the onset of an episode the patient becomes . Onset of symptoms associated with this disorder is extremely rapid. The change of episode duration with IV-MP (vs previous episode duration) was . {{configCtrl2.info.metaDescription}} This site uses cookies. This sleepiness is unlike the drowsiness of a person who got too little sleep, it is far more severe. Kleine-Levin syndrome (KLS) is a recurrent hypersomnia that is characterized by recurrent (relapsing-remitting) episodes of severe hypersomnolence separated by intervening periods of normal behavior, in association with cognitive, psychiatric, and behavioral disturbances ( Table 8.4 ). Kleine-Levin syndrome (KLS) is a rare disorder characterized by persistent episodic hypersomnia and cognitive or mood changes. Because of . Genetics. Kleine-Levin syndrome (KLS) is a rare neurological disorder primarily affecting young subjects. Methods A total of 26 patients with KLS received 1 g/d IV-MP for 3 days during 1 to 6 episodes each (totaling 43 IV-MP sessions). Symptoms occur in cycles that can last anywhere from a few days to several weeks. A few studies mention cases that occurred in Africa, especially in Côte d'Ivoire. Kleine-Levin syndrome is an extremely rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), excessive eating (compulsive hyperphagia), and behavioral abnormalities. Symptoms occur as "episodes," typically lasting a few days to a few weeks. Kleine-Levin Syndrome (KLS) is a central disorder of hypersomnolence with periods of severe sleepiness and periods of normal sleep. Primarily affecting adolescent males (though it can affect anyone), Kleine-Levin syndrome is a disorder marked by episodes lasting a few days to a few weeks. Kleine-Levin Syndrome (KLS) is a neurological and sleep disorder that's most common amongst adolescent males (around 70% of those with this condition are male). " Kleine-Levin Syndrome (KLS) is a rare and complex neurological disorder characterized by recurring periods of excessive amounts of sleep, altered behavior, and a reduced understanding of the world. Patient are not able to perform their daily work, and are consumed by lethargy. This article reviews the current available research and describes common . What causes Kleine Levin Syndrome? KLS is a rare disorder, with an estimated prevalence of 1 . IAmA 31M with Kleine-Levin Syndrome (KLS) aka Sleeping Beauty Syndrome. Visit: www.alannawonglife.comAlanna Wong was featured in a BBC documentary in 2008. During these episodes, people with Kleine-Levin syndrome can experience: Excessive sleep (up to 20 hours a day) Because of this, KLS is also known as Sleeping Beauty Syndrome. Kleine-Levin syndrome is an extremely rare disorder characterized by the need for excessive amounts of sleep (hypersomnolence), excessive eating (compulsive hyperphagia), and behavioral abnormalities. Symptoms are intermittent, coming and going in phases for months or years at a time. Kleine Levin Syndrome is a sleeping disorder in which a person feels very sleepy and sleeps for most of the day and night. Symptoms occur as "episodes," typically lasting a few days to a few weeks. The Kleine-Levin Syndrome is a differential diagnosis for patients with diurnal excessive sleepiness and a suspicion of narcolepsy. Kleine-Levin syndrome, or KLS, is a rare disorder associated with extreme fatigue and excessive sleepiness, causing patients to sleep as much as 20 hours a day. The disorder primarily affects adolescent males. Background: Kleine-Levin syndrome (KLS) is a rare disorder of unknown etiology. I also have a daughter that was diagnosed with narcolepsy at around age 16-17, but had symptoms years prior to being diagnosed. Symptoms occur as "episodes," typically lasting a few days to a few weeks. Kleine-Levin syndrome is a recurrent hypersomnia associated with symptoms of hyperphagia, hypersexuality, and cognitive impairment. Kleine-Levin syndrome (KLS), also known as "Sleeping beauty syndrome," is a rare yet devastating parasomnia that includes recurrent episodes of hypersomnia, along with behavioral or cognitive abnormalities, coupled with compulsive eating and hypersexuality. Background. Scientists and doctors do not know the exact cause of Kleine Levin Syndrome, but there are a few factors that could possibly increase your risk: A hypothalamus injury, which is the part of the brain responsible for controlling sleep, body temperature and appetite. Symptoms occur as "episodes," typically lasting a few days to a few weeks. . Hypersomnia means excessive sleepiness. Objective: To systematically investigate patients with KLS with reference to the available hypotheses. Kleine-Levin syndrome, also sometimes referred to as Sleeping Beauty syndrome is a rare neurological disorder that involves episodes of excessive sleep and altered behavior. 1 Usually affecting adolescent males, episodes normally last up to a few weeks and terminates with total and spontaneous recovery. A person with this problem finds it impossible to care for himself and . Symptoms may last for days to weeks, include excessive food intake, irritability, disorientation, lack of energy and hypersensitivity to noise. Kleine-Levin syndrome is characterized as a recurring but reversible need for excessive sleep (up to 20 hours per day), excessive food intake, and behavior changes such as an uninhibited sex drive, irritability, and low energy. We collected detailed clinical data and blood samples on 108 patients, 79 parent pairs, and 108 matched control subjects. The documentary is on rare neurological conditions. It is characterized by recurring but reversible periods of excessive sleep (up to 20 hours per day). People with this condition can sleep for up to twenty hours a day for many days only waking . Other symptoms include . Kleine Levin syndrome (KLS) is a neurological condition and sleep disorder where one has severe excessive daytime sleepiness (EDS), accompanied by sudden and pronounced changes in behavior. It is characterized by relapsing-remitting episodes of hypersomnia in association with cognitive and behavioral disturbances. Learn about Kleine-Levin syndrome, a disorder characterized by recurring episodes of excessive sleep (up to 20 hours per day). Even after taking long naps, the individual does not feel rested. The KLS Foundation exchanges information among patients, their families, and . Sleeping Beauty Syndrome is a neurological disorder that causes excessive sleepiness, altered mood, and unusual behavior. The disorder strikes adolescents primarily but can occur in younger children and adults. Abbreviation: KLS See more. It is characterized by recurring but reversible periods of excessive sleep (up to 20 hours per day). The onset of an episode starts with drowsiness followed by sleep for most of the days and nights this is known as Hyper somnolence. Such symptoms may persist for days to weeks. Many patients also experience hyperphagia, hypersexuality and other symptoms. The disorder strikes adolescents primarily but can occur in younger children and adults. Kleine-Levin Syndrome (KLS) is a rare and complex disorder characterized by recurring periods of excessive sleep, as well as altered cognition and behavior. In some cases, this means up to 20 hours a day are spent sleeping. Kleine-Levin Syndrome . Associated symptoms include an abnormally uninhibited sex drive, irritability, and disorientation. This article reviews the current available research and describes common clinical symptoms, differential diagnosis, and acceptable workup and treatment. Such symptoms may persist for days to weeks. Kleine Levin syndrome is a rare illness typically presenting with periods of hypersomnia, megaphagia, hypersexuality and other cognitive and behavioural disturbances. {{configCtrl2.info.metaDescription}} This site uses cookies. Posted by kaseykalb @kaseykalb, Sep 4, 2018. Kleine-levin syndrome definition, prolonged episodes of excessive sleepiness often accompanied by overeating, hallucinations, and electroencephalogram changes, usually beginning in adolescence. During episodes, sufferers often require more than 15 hours of sleep per day and experience other symptoms, such as irritability, confusion, and disinhibition.. Kleine Levin syndrome (KLS) is a rare neurological disorder characterized by episodes of the excessive need for sleep that occur weeks or months apart. The episode of Kleine Levin Syndrome may continue for 10 years and more. Kleine-Levin syndrome is most commonly found in adolescent males. These episodes alternate from periods without any symptoms and normal sleep & behavior lasting months to years. These episodes of needing extra sleep can occur multiple times in a year but eventually subside over time. Onset of symptoms associated with this disorder is extremely rapid. During episodes, sufferers often require more than 15 hours of sleep per day, hence it is also called sleeping beauty syndrome. It is characterized by recurring but reversible periods of excessive sleep (up to 20 hours per day). It is uncommon for patients beyond 30 years old years to give their first scene, Kleine-Levin Disorder [KLS] is an uncommon and, in spite of the fact that cases have been issue portrayed by intermittent scenes of . Adolescent males are the predominant victims of the disorder. Kleine-Levin Syndrome. KLS is a rare and complex neurological disorder characterized by recurring periods of excessive amounts of sleep, altered behavior, and a reduced understanding of the world where the patient becomes progressively drowsy and sleeps for most of the day and night, sometimes waking only to eat or use the bathroom. Subscribe if you like the video!0:00 - Background Info0:25 - Clinical Features2:13 - Evaluation3:13 - Treatment3:53 - Prognosis This has been an on going battle for over 3 years now. Getting a proper diagnosis of this condition can be a challenge since its main symptom (hypersomnia) is also a common symptom in a number of other conditions as well. I sometimes sleep for months at a time. It is characterized by recurring but reversible periods of excessive sleep (up to 20 hours per day). Kleine-Levin syndrome (KLS) is a rare sleep disorder mainly affecting teenage boys in which the main features are intermittent hypersomnolence, behavioral and cognitive disturbances, hyperphagia, and in some cases hypersexuality. KLEINE-LEVIN SYNDROME: "Kleine Levin Syndrome is a rare disorder primarily occurring in adolescent males." The disease mainly affects young males. In addition to sleepiness, individuals also have compulsive overeating and hyper-sexuality. Kleine-Levin syndrome (KLS) is a rare disorder in which affected people experience episodes at least once per year during which they sleep for at least 11 hours out of every day (but often for days at a time), eat excessively (), have abnormal thinking and behavior, and are hypersexual.Between episodes, their alertness, behavior, and thinking are normal. Kleine-Levin syndrome: [ klīn´ĕ lev´in ] episodic periods of excessive sleep and overeating lasting for several weeks, usually in adolescent boys. Symptoms are intermittent, coming and going in phases for months or years at a time. Methods. Kleine Levin syndrome is a rare disorder characterized by recurrent episodes of excessive sleep (hypersomnia) along with cognitive and behavioral changes. Kleine-Levin Syndrome (KLS) is a type of recurrent hypersomnia.People with KLS experience episodes of excessive sleeping that last between a few days and a few weeks.They may need to sleep as many as 20 hours a day. Each episode lasts for one or two weeks, and affected people are entirely asymptomatic between episodes. KLS is most common in adolescent and young adult males. It is part of the brain that governs appetite and sleep. Keywords: Kleine-Levin syndrome, Hypersomnia, hyper sexuality, megaphagia, periodic recurrent INTRODUCTION than young ladies. Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male). Kleine-Levin syndrome. Kleine-Levin Syndrome (KLS) is a rare and complex neurological disorder characterized by recurring periods of excessive amounts of sleep, altered behavior, and a reduced understanding of the world. These episodes usually last for a few days to a few weeks. The disorder strikes adolescents primarily but can occur in younger children and adults. The exact prevalence of KLS is unknown but is estimated to be around 1 in a million. This disorder is characterized by persistent episodic hypersomnia. Kleine-Levin syndrome is a rare disorder characterized by relapsing‐remitting episodes of hypersomnia, cognitive disturbances, and behavioral disturbances, such as hyperphagia and hypersexuality. Alanna Wong shares wh. In this paper, we report the very first two cases observed in the . More to Know. Case-reports, small series, meta-analysis and a recent large, prospective trio study are consistent with a homogeneous . Etiology is unknown, and there is no specific clinical or imaging test for this syndrome even though the illness . Excessive sleepiness is the cardinal symptom of KLS. Possibly first reported by Brierre de Bosmont in 1862, the condition however received . Kleine-Levin syndrome is a rare disorder that primarily affects adolescent males (approximately 70 percent of those with Kleine-Levin syndrome are male).
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